Anti-Phospho-Tau(S396) Antibody [SN62-09]

ET1611-68

Anti-Phospho-Tau(S396) Antibody [SN62-09]

Tau, also known as MAPT (microtubule-associated protein tau), MAPTL, MTBT1 or TAU, is a 758 amino acid protein that localizes to the cytoplasm, as well as to the cytoskeleton and the cell membrane, and contains four Tau/MAP repeats. Expressed in neuronal tissue and existing as multiple alternatively spliced isoforms, Tau functions to promote microtubule assembly and stability and is thought to be involved in the maintenance of neuronal polarity. Tau may also link microtubules with neural plasma membrane components and, in addition to its role in microtubule stability, is also necessary for cytoskeletal plasticity. Tau is highly subject to a variety of post-translational modifications, including phosphorylation on serine and threonine residues, polyubiquitination (and subsequent proteasomal degradation) and glycation of specific Tau isoforms. Defects in the gene encoding Tau are associated with Alzheimers disease, pallido-ponto-nigral degeneration (PPND), corticobasal degeneration (CBD) and progressive supranuclear palsy (PSP).

496.5 €

STJ11101031

Anti-Phospho-Tau-S519/T522 antibody

This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.

857.4 €

STJ11101134

Anti-Phospho-Tau-Ser404 antibody

857.4 €

MBS1569083-5x01mg

Anti-Phospho-Tau (pS396/pS404) Antibody

2123 €

P00097

Anti-Phospho-Tau (Ser416) MAPT Antibody

Boster Bio Anti-Phospho-Tau (Ser416) MAPT Antibody (Catalog # P00097). Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

847.5 €

GB114488

Anti-Phospho-Tau (T231) Rabbit pAb

380 €