Anti-Phospho-Histone H3.3 (S31) Antibody [JE62-92]

HA721034

Anti-Phospho-Histone H3.3 (S31) Antibody [JE62-92]

Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

496.5 €

STJ11101036

Anti-Phospho-Histone H4-S1 antibody

857.4 €

STJ11100980

Anti-Phospho-Histone H3-S28 antibody

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.

857.4 €

MBS1752408-01mL

Anti-Phospho-Histone H2A.X (S139) Monoclonal Antibody

758.75 €

MBS1752408-5x01mL

Anti-Phospho-Histone H2A.X (S139) Monoclonal Antibody

2569.25 €

P09849

Anti-Phospho-Histone H1 (Thr17) Polyclonal Antibody

Boster Bio Anti-Phospho-Histone H1 (Thr17) Polyclonal Antibody (Catalog # P09849). Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

690 €