RecombinantBetacellulin,Mouse(HEK293-expressed)
406.5 EUR
In Stock
quantity
Produktdetaljer
Katalognummer: 965 - BK0299
Produktkategori: Företag och industri > Vetenskap och laboratorium
Gentaur
Storlek: 10μg
Parameters
| Additional information | Betacellulin, also known as BTC, belongs to the EGF family of growth factors. It is expressed in many tissues, such as kidney, pancreas and small intestine. Betacellulin is initially synthesized as a membrane-bound precursor containing multiple EGF-like domains in its extracellular region, and is released from the membrane by proteolytic cleavage. BTC is the ligand for EGFR/ErbB receptor tyrosine kinases, and plays a role in cell growth and differentiation. BTC has been reported to promote beta cell growth and differentiation in the pancreas. Pancreas-specific expression of this gene may induce islet neogenesis and remediate hyperglycemia in type I diabetes. |
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BK0299
RecombinantBetacellulin,Mouse(HEK293-expressed)
ED50 <0.08ng/ml, measured in a cell proliferation assay using 3T3 cells.
406.5 €
BK0299
RecombinantBetacellulin,Mouse(HEK293-expressed)
ED50 <0.08ng/ml, measured in a cell proliferation assay using 3T3 cells.
132 €
BK0009
RecombinantBetacellulin,Mouse
ED50 <0.5ng/mL, measured by a cell proliferation assay using3T3cells, corresponding to a specific activity of>2× 10ˆ6 units/mg.
406.5 €
BK0253
RecombinantIL-6,Human(CHO-expressed)
ED50 < 0.06 ng/ml, measured in a cell proliferation assay using 7TD1 cells.
406.5 €
BK0253
RecombinantIL-6,Human(CHO-expressed)
ED50 < 0.06 ng/ml, measured in a cell proliferation assay using 7TD1 cells.
132 €
96-519
LIF Recombinant Protein (HEK293 Expressed)
Leukemia inhibitory factor, or LIF, an interleukin 6 class cytokine, is a protein in cells that affects cell growth and development.Leukemia Inhibitory Factor has several functions such as cholinergic neuron differentiation, control of stem cell pluripotency, bone & fat metabolism, mitogenesis of factor dependent cell lines & promotion of megakaryocyte production in vivo. Removal of LIF pushes stem cells toward differentiation, but they retain their proliferative potential or pluripotency. Therefore LIF is used in mouse embryonic stem cell culture. It is necessary to maintain the stem cells in an undifferentiated state, however genetic manipulation of embryonic stem cells allows for LIF independent growth, notably overexpression of the gene Nanog. LIF is not required for culture of human embryonic stem cells.
832.9 €
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