Phospho-MLKL (S358) Recombinant Monoclonal Antibody [4A6]

A74191

Phospho-MLKL (S358) Recombinant Monoclonal Antibody [4A6]

608.5 €

BS79507

Phospho-MLKL-S358 polyclonal antibody

1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

398 €

AP1244

Phospho-MLKL-S358 Rabbit pAb

This gene belongs to the protein kinase superfamily. The encoded protein contains a protein kinase-like domain; however, is thought to be inactive because it lacks several residues required for activity. This protein plays a critical role in tumor necrosis factor (TNF)-induced necroptosis, a programmed cell death process, via interaction with receptor-interacting protein 3 (RIP3), which is a key signaling molecule in necroptosis pathway. Inhibitor studies and knockdown of this gene inhibited TNF-induced necrosis. High levels of this protein and RIP3 are associated with inflammatory bowel disease in children. Alternatively spliced transcript variants have been described for this gene.

1249.95 €

JOT-MCA1026-50ul

phospho-MLKL (S358) mouse Monoclonal Antibody(6F8)

366 €

EM1320-100ul

phospho-MLKL (S358) (6B4) Mouse Monoclonal Antibody

IHC

953 €

EM1320-50ul

phospho-MLKL (S358) (6B4) Mouse Monoclonal Antibody

IHC

878 €