Palbociclib-propargyl

HY-130296

Palbociclib-propargyl

Palbociclib-propargyl is a ligand for target protein CDK6 for PROTAC, and binds to CRBN ligand via a PEG linker to make a PROTAC CP-10. CP-10 shows a DC50 of 2.1 nM for CDK6[1]. Palbociclib-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

1207.88 €

T18515-10mg

Palbociclib-propargyl

Palbociclib-propargyl

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T18515-1g

Palbociclib-propargyl

Palbociclib-propargyl

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106610

Palbociclib Isethionate

435 €

HY-A0065

Palbociclib (isethionate)

Palbociclib (PD 0332991) isethionate is an orally active selective CDK4 and CDK6 inhibitor with IC50 values of 11 and 16 nM, respectively. Palbociclib isethionate has potent anti-proliferative activity and induces cell cycle arrest in cancer cells, which can be used in the research of HR-positive and HER2-negative breast cancer and hepatocellular carcinoma[1][3][4].

579.3 €

T6240-10mg

Palbociclib Isethionate

Palbociclib Isethionate

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