Native Porcine Catechol-O-methyl Transferase
764 EUR
In Stock
quantity
Produktdetaljer
Katalognummer: 501 - NATE-0148
Produktkategori: Företag och industri > Vetenskap och laboratorium
Gentaur
Storlek: 5 mg
Parameters
| Storage and shipping | −20°C |
|---|
NATE-0148
Native Porcine Catechol-O-methyl Transferase
Catechol-O-methyltransferase (COMT; EC 2.1.1.6) is one of several enzymes that degrade catecholamines such as dopamine, epinephrine, and norepinephrine. In Humans, catechol-O-methyltransferase protein is encoded by the COMT gene. As the regulation of catecholamines is impaired in a number of medical conditions, several pharmaceutical drugs target COMT to alter its activity and therefore the availability of catecholamines. COMT was first discovered by the biochemist Julius Axelrod in 1957.
764 €
NATE-0144
Native Porcine Colipase
Colipase is a protein co-enzyme required for optimal enzyme activity of pancreatic lipase. It is secreted by the pancreas in an inactive form, procolipase, which is activated in the intestinal lumen by trypsin. Its function is to prevent the inhibitory effect of bile salts on the lipase-catalyzed intraduodenal hydrolysis of dietary long-chain triglycerides. In humans, the colipase protein is encoded by the CLPS gene.
776 €
NATE-1869
Native Porcine Creatine Phosphokinase: > 300 U/mg protein,
Creatine phosphokinase (CPK) is widely distributed and is primarily involved with ATP regeneration in conjunction with the contractile and transport systems. The enzyme is dimeric and exists in three isoenzyme forms: MM (muscle), MB (heart) and BB (brain). CPK from rabbit muscle has a molecular weight of 81,000 The hybrid isoenzyme (MB) has the highest concentration in the heart muscle. Therefore, determination of the serum CPK level of this isoenzyme has been used as a sensitive index for the diagnosis of myocardial infarction. Elevated levels of the BB isoenzyme of CPK have been reported in the serum of patients immediately following cardiac surgery. The CPK-BB levels in serum returned to normal by the fourth post-operative day. This may be a more sensitive diagnostic tool than the serum levels of CPK-MB isoenzyme in cardiac patients.
572 €
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