![iFluor™ 488 Conjugated Anti-CD47 Antibody [1B1]](/images/no-image-product-box.jpg "iFluor™ 488 Conjugated Anti-CD47 Antibody [1B1]")
iFluor™ 488 Conjugated Anti-CD47 Antibody [1B1]
504.58 EUR
In Stock
quantity
Produktdetaljer
Katalognummer: 992 - HA600104F
Produktkategori: Företag och industri > Vetenskap och laboratorium
Gentaur
Storlek: 100ul
Parameters
| Additional information | Recombinant protein within human CD47 aa 19-141 (Extracellular). |
|---|---|
| Storage and shipping | Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles. |
HA600104F
iFluor™ 488 Conjugated Anti-CD47 Antibody [1B1]
CD47 is an integral membrane protein that plays a role in the regulation of cation fluxes across cell membranes. Specifically, CD47 is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to the extracellular matrix. It is also a receptor for the C-terminal cell binding domain of thrombospondin (SIRP). Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. CD47 is absent from Rh-null erythrocytes, but does play a role in cell adhesion in non-erythroid cells and may prevent premature elimination of erythrocytes. It may also be involved in membrane permeability changes following viral infection. Plays an important role in memory formation and synaptic plasticity in the hippocampus (By similarity). Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integrin dependent signal transduction. May prevent premature elimination of red blood cells. May be involved in membrane permeability changes induced following virus infection. CD47 is expressed on hemopoietic cells, epithelial cells, endothelial cells and fibroblasts and is strongly expressed in brain and mesenchymal cells.
504.58 €
10471050-100tests
iFluor® 488 Anti-human CD47 Antibody *HI172*
HI172 is an anti-human monoclonal antibody that is specific for the CD47 antigen.
495.26 €
10471051-500tests
iFluor® 488 Anti-human CD47 Antibody *HI172*
HI172 is an anti-human monoclonal antibody that is specific for the CD47 antigen.
1504.76 €
10471010-100tests
iFluor® 350 Anti-human CD47 Antibody *HI172*
HI172 is an anti-human monoclonal antibody that is specific for the CD47 antigen.
495.26 €
10471011-500tests
iFluor® 350 Anti-human CD47 Antibody *HI172*
HI172 is an anti-human monoclonal antibody that is specific for the CD47 antigen.
1504.76 €
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