FM-479
0.01 EURAsk for quotation
On request
quantity
Produktdetaljer
Katalognummer: 931 - T22333-5mg
Produktkategori: Företag och industri > Vetenskap och laboratorium
Gentaur
Storlek: 5mg
Parameters
| Additional information | SMILES: N#CC(=CC=1OC(=CC1)C2=NC3=CN=C4C(C=CN4C)=C3N2C5CCCCC5)C(=O)N(C)C; Formula: C25H26N6O2 |
|---|
HY-131014
FM-479
FM-479 is the negative control of FM-381 (HY-102046) and has no activity on JAK3 or other kinases[1]. FM-381 is a potent covalent reversible inhibitor of JAK3 targeting the unique Cys909. FM-381 has an IC50 of 127 pM for JAK3, with 410, 2700 and 3600-fold selectivity over JAK1, JAK2 and TYK2, respectively.
Ask for quotation
HY-15672
FM19G11
FM19G11 is a hypoxia-inducible factor-1-alpha (HIF-1α) inhibitor, and it inhibits hypoxia-induced luciferase activity with an IC50 of 80 nM in HeLa cells. FM19G11 modulates other signaling pathways, including mTOR and PI3K/Akt/eNOS, when the HIF-1α pathway is inactivated under normoxic conditions[1][2].
1129.95 €
Håll dig uppdaterad! Visa tidigare publikationer
By: Author , 2 Comment
Pneumokocker – vad är det som angriper våra barn?
30 August 2025
By: Author , 2 Comment
Anaplasmos hos hundar och katter – allt du behöver veta
23 August 2025
By: Author , 2 Comment
Solbränna – hur leker man säkert i solen?
16 August 2025
By: Author , 2 Comment
Stroke – viktig information
8 August 2025