FM-381
1875 EUR
In Stock
quantity
Produktdetaljer
Katalognummer: 940 - 407443
Produktkategori: Företag och industri > Vetenskap och laboratorium
Gentaur
Storlek: 100.0mg
Parameters
| Additional information | Smiles Code: O=C(N(C)C)/C(C#N)=C/C(O1)=CC=C1C2=NC3=CN=C(NC=C4)C4=C3N2C5CCCCC5 |
|---|
HY-102046
FM-381
FM-381 is a potent covalent reversible inhibitor of JAK3 targeting the unique Cys909. FM-381 has an IC50 of 127 pM for JAK3, with 410, 2700 and 3600-fold selectivity over JAK1, JAK2 and TYK2, respectively.
857.22 €
HY-15672
FM19G11
FM19G11 is a hypoxia-inducible factor-1-alpha (HIF-1α) inhibitor, and it inhibits hypoxia-induced luciferase activity with an IC50 of 80 nM in HeLa cells. FM19G11 modulates other signaling pathways, including mTOR and PI3K/Akt/eNOS, when the HIF-1α pathway is inactivated under normoxic conditions[1][2].
1129.95 €
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