Anti-Ubiquitin D Antibody [JJ084-09]

ET1701-9

Anti-Ubiquitin D Antibody [JJ084-09]

FAT10, also designated Ubiquitin D or Diubiquitin, is a 165 amino acid protein encoded in the major histocompatibility complex (MHC) that consists of two domains which share significant homology with ubiquitin. Each domain contains two cysteines, along with a free C-terminal diglycine motif required for FAT10 conjugate formation. FAT10 is inducible by interferon-g and tumor necrosis factor a (TNF?). The FAT10 protein interacts with MAD2, a component of the spindle checkpoint, and plays a role in antigen presentation, cytokine response, apoptosis and mitosis. It may also regulate cell growth during dendritic cell or B cell activation and development. FAT10 mRNA is expressed mainly in some dendritic cells and lymphoblastoid lines and in other specific cells subsequent to interferon-g induction. The human FAT10 gene, designated UBD, maps to chromosome 6p21.3 and is overexpressed in the tumors of various epithelial cancers.

496.5 €

AB0144-200

Anti-Ubiquitin

Goat polyclonal antibody to Ubiquitin. Ubiquitin is a highly conserved of about 8.5 kDa regulatory protein expressed in all eukaryotic tissues. Its function is labelling of proteins for degradation through ubiquitin proteasome system. In order to perform this function, the protein to be degraded is first covalently attached to the C terminus of ubiquitin, and a complex of degradative enzymes then recognizes the ubiquitinated complex.

535 €

MBS448084-06mg

Anti-Ubiquitin

586.62 €

1107NF-v2015

Rabbit anti-Ubiquitin

1830.85 €

AUB01-HRP

Anti-Ubiquitin-HRP Antibody

820.72 €

AUB01-HRP-S

Anti-Ubiquitin-HRP Antibody

327.76 €