Anti-Noggin Antibody

YF-MA16737

Anti-Noggin (3A2)

Mouse monoclonal to Noggin

803.4 €

YF-MA16738

Anti-Noggin (4A1)

Mouse monoclonal to Noggin

803.4 €

0805-2

Anti-Noggin Antibody

Noggin is a signaling molecule that plays an important role in promoting somite patterning in the developing embryo. It is released from the notochord and regulates bone morphogenic protein (BMP4) during development. The absence of BMP4 will cause the patterning of the neural tube and somites from the neural plate in the developing embryo. It also causes formation of the head and other dorsal structures. Noggin function is required for correct nervous system, somite, and skeletal development. Experiments in mice have shown that noggin also plays a role in learning, cognition, bone development, and neural tube fusion. Heterozygous missense mutations in the noggin gene can cause deformities such as joint fusions and syndromes such as multiple synostosis syndrome (SYNS1) and proximal symphalangism (SIM1). SYNS1 is different from SYM1 by causing hip and vertebral fusions. The embryo may also develop shorter bones, miss any skeletal elements, or lack multiple articulating joints. Increased plasma levels of Noggin have been observed in obese mice and in patients with a body mass index over 27. Additionally, it has been shown that Noggin depletion in adipose tissue leads to obesity.

433.5 €

MBS9239964-5x01mL

Anti-Nogo Antibody

2532.27 €

STJ94527

Anti-Nogo A antibody

Rabbit polyclonal to Nogo A.

504.6 €

A01844

Anti-NogoA RTN4 Antibody

Boster Bio Anti-NogoA RTN4 Antibody (Catalog # A01844). Tested in ELISA, WB, IHC-P, ICC, IF applications. This antibody reacts with Human, Mouse, Rat.

823.5 €