Anti-ERBB3 antibody

PAab02828

Anti-ERBB3 antibody

17081 €

PAab02828

Anti-ERBB3 antibody

755.84 €

STJ27527

Anti-ERBB3 antibody

This gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation of pathways which lead to cell proliferation or differentiation. Amplification of this gene and/or overexpression of its protein have been reported in numerous cancers, including prostate, bladder, and breast tumors. Alternate transcriptional splice variants encoding different isoforms have been characterized. One isoform lacks the intermembrane region and is secreted outside the cell. This form acts to modulate the activity of the membrane-bound form. Additional splice variants have also been reported, but they have not been thoroughly characterized.

648.6 €

ADC-W-2367

Anti-ERBB3 (Duligotuzumab)-SPDB-DM4 ADC

This ADC product is comprised of an anti-ERBB3 monoclonal antibody conjugated via a SPDB linker to DM4

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A00010

Anti-erbB-2 Antibody

Boster Bio Anti-erbB-2 Antibody (Catalog # A00010). Tested in ELISA, WB, IHC-P, IF, IP applications. This antibody reacts with Human, Mouse, Rat.

823.5 €

STJ92973

Anti-ErbB-3 antibody

Rabbit polyclonal to ErbB-3.

504.6 €