YM-244769
414.5 EUR
414.5 EUR
In Stock
quantity
Produktdetaljer
Katalognummer: 544 - MBS5786623-1mg
Produktkategori: Företag och industri > Vetenskap och laboratorium
Leverantör:
Gentaur
Storlek: 1(mg
Parameters
| Storage and shipping | Powder: -2 degree C for 3 years;In solvent: -80 degree C for 2 years |
|---|
HY-136182A
YM-244769
YM-244769 is a potent, selective and orally active Na+/Ca2+ exchanger (NCX) inhibitor. YM-244769 preferentially inhibits NCX3 and suppresses the unidirectional outward NCX current (Ca2+ entry mode), with IC50s of 18 nM and 50 nM, respectively. YM-244769 efficiently protects against hypoxia/reoxygenation-induced SH-SY5Y neuronal cell damage. YM-244769 can also increase urine volume and urinary excretion of electrolytes in mice[1][2][3].
740.34 €
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