SLP-76 Polyclonal Antibody
366 EUR
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quantity
Produktdetaljer
Katalognummer: 965 - JOT-AP08366-50ul
Produktkategori: Företag och industri > Vetenskap och laboratorium
Gentaur
Storlek: 50ul
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| Additional information | SLP-76 was originally identified as a substrate of the ZAP-70 protein tyrosine kinase following T cell receptor (TCR) ligation in the leukemic T cell line Jurkat. The SLP-76 locus has been localized to human chromosome 5q33 and the gene structure has been partially characterized in mice. The human and murine cDNAs both encode 533 amino acid proteins that are 72% identical and comprised of three modular domains. The NH2-terminus contains an acidic region that includes a PEST domain and several tyrosine residues which are phosphorylated following TCR ligation. SLP-76 also contains a central proline-rich domain and a COOH-terminal SH2 domain. A number of additional proteins have been identified that associate with SLP-76 both constitutively and inducibly following receptor ligation, supporting the notion that SLP-76 functions as an adaptor or scaffold protein. Studies using SLP-76 deficient T cell lines or mice have provided strong evidence that SLP-76 plays a positive role in promoting T cell development and activation as well as mast cell and platelet function. |
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ABP52802-003ml
SLP-76 Polyclonal Antibody
A polyclonal antibody for detection of SLP-76 from Human, Mouse, Rat. This SLP-76 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human SLP-76 at AA range: 270-350
464.4 €
ABP52802-01ml
SLP-76 Polyclonal Antibody
A polyclonal antibody for detection of SLP-76 from Human, Mouse, Rat. This SLP-76 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human SLP-76 at AA range: 270-350
700.2 €
ABP52802-02ml
SLP-76 Polyclonal Antibody
A polyclonal antibody for detection of SLP-76 from Human, Mouse, Rat. This SLP-76 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human SLP-76 at AA range: 270-350
925.2 €
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