SKF-83566
188.38 EUR
In Stock
quantity
Produktdetaljer
Katalognummer: 804 - HY-103430A
Produktkategori: Företag och industri > Vetenskap och laboratorium
Gentaur
Storlek: 10 mg
Parameters
| Storage and shipping | -20°C, 3 years; 4°C, 2 years (Powder) |
|---|
HY-103430A
SKF-83566
SKF-83566 is a potent, blood-brain permeable and orally active D1-like dopamine receptor (D1DR) antagonist and a weaker competitive antagonist at the vascular 5-HT2 receptor (Ki=11 nM)[1][3]. SKF-83566 is a competitive DAT (dopamine transporter) inhibitor with an IC50 of 5.7 μM[2]. SKF-83566 also shows selective inhibition for adenylyl cyclase 2 (AC2) over AC1 and AC5 in the isolated rabbit thoracic aorta[4]. SKF-83566 can be used for research of parkinson’s disease and nicotine craving alleviation[5].
188.38 €
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