SARS-CoV-2-IN-32
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On request
quantity
Produktdetaljer
Katalognummer: 931 - T63181-1g
Produktkategori: Företag och industri > Vetenskap och laboratorium
Gentaur
Storlek: 1g
Parameters
| Additional information | SMILES: Cc1nn(c(O)c1C(c1c(C)nn(c1O)-c1ccccc1)c1ccc(cc1)[N+]([O-])=O)-c1ccccc1; Formula: C27H23N5O4 |
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HY-151477
SARS-CoV-2-IN-32
SARS-CoV-2-IN-32 (compound 3g) is a COVID-19 inhibitor. SARS-CoV-2-IN-32 shows anti-proliferative activity against cancer cells. SARS-CoV-2-IN-32 exhibits comparatively high binding affinity (-8.8 Kcal/mole) to COVID-19 main protease (Mpro) (PDB ID: 6LU7). SARS-CoV-2-IN-32 can be used in studies of cancer and COVID-19[1].
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HY-144771
SARS-CoV-2-IN-14
SARS-CoV-2-IN-14 (compound 6) is a potent inhibitor of SARS-CoV-2 with an IC50 of 0.39 μM. SARS-CoV-2-IN-14 is a niclosamide analogue. SARS-CoV-2-IN-14 contains higher stability in human plasma and liver S9 enzymes assay than niclosamide, which can improve bioavailability and half-life when administered orally[1].
129.93 €
HY-144772
SARS-CoV-2-IN-15
SARS-CoV-2-IN-15 (compound 11) is a potent inhibitor of SARS-CoV-2 with an IC50 of 0.49 μM. SARS-CoV-2-IN-15 is a niclosamide analogue. SARS-CoV-2-IN-15 contains higher stability in human plasma and liver S9 enzymes assay than niclosamide, which can improve bioavailability and half-life when administered orally[1].
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HY-145276
SARS-CoV-2-IN-10
SARS-CoV-2-IN-10 is a potent and nontoxic inhibitor of SARS-CoV-2 3CL protease (3CLpro) with an IC50 and EC50 of 0.13 and 1.03 nM, respectively. SARS-CoV-2 3C-like protease (3CLpro), an enzyme essential for viral replication, is an attractive target for intervention. SARS-CoV-2-IN-11 may lead to the emergence of effective SARS-CoV-2-specific antivirals[1].
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