RecombinantFGF-8c,Mouse
406.5 EUR
In Stock
quantity
Produktdetaljer
Katalognummer: 965 - BK0046
Produktkategori: Företag och industri > Vetenskap och laboratorium
Gentaur
Storlek: 10μg
Parameters
| Additional information | Fibroblast Growth Factor 8c (FGF-8c) is a cytokine belonging to the heparin-binding FGF family, which has at least 23 members. In different species, e.g. human and mouse, FGF-8 has 8 different isoforms, from FGF-8a to FGF-8h. Different FGF-8 isoforms have different affinities to the receptors, thus conduct different signaling cascade pathways. FGF-8 has very widespread expression pattern during embryonic development, and is an organizer and inducer for gastrulation, somitogenesis, morphogenesis, and limb induction. However, FGF-8 is also a potential oncogene: in normal adult cells, FGF-8 has very low expression; on the other hand, FGF-8 is highly expressed in cancer cells of breast, prostate, and ovarian tumors. FGF-8 promotes tumor angiogenesis by increasing neovascularization, and induces osteoblastic differentiation.Recombinant mouse Fibroblast Growth Factor 8c (rmFGF-8c) produced in E.coli is a single non-glycosylated polypeptide chain containing 247 amino acids. A fully biologically active molecule, rmFGF-8c has a molecular mass of 28.2 kDa analyzed by reducing SDS-PAGE and is obtained by proprietary chromatographic techniques at GenScript. |
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BK0046
RecombinantFGF-8c,Mouse
ED50 < 150 ng/mL, measured by a cell proliferation assay using 3T3 cells, corresponding to a specific activity of > 6.7× 10ˆ3 units/mg.
406.5 €
BK0046
RecombinantFGF-8c,Mouse
ED50 < 150 ng/mL, measured by a cell proliferation assay using 3T3 cells, corresponding to a specific activity of > 6.7× 10ˆ3 units/mg.
132 €
BK0039
RecombinantFGF-18,Rat
ED50 < 0.5 µg/mL, measured by a cell proliferation assay using 3T3 cells, corresponding to a specific activity of > 2× 10ˆ3 units/mg.
406.5 €
BK0053
RecombinantFGF-basic(145aa),Human
ED50 < 0.25 ng/mL, measured by the cell proliferation assay using 3T3 cells, corresponding to a specific activity of > 4 × 10ˆ6 units/mg
132 €
BK0054
RecombinantFGF-basic(146aa),Human
ED50 < 0.25 ng/mL, measured by the cell proliferation assay using 3T3 cells, corresponding to a specific activity of > 4 × 10ˆ6 units/mg.
406.5 €
BK0054
RecombinantFGF-basic(146aa),Human
ED50 < 0.25 ng/mL, measured by the cell proliferation assay using 3T3 cells, corresponding to a specific activity of > 4 × 10ˆ6 units/mg.
132 €
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