Recombinant Mouse ITK Kinase Protein (aa 351-619, His & GST tag)
2907.12 EUR
In Stock
quantity
Produktdetaljer
Katalognummer: 544 - MBS2547018-5x005mg
Produktkategori: Företag och industri > Vetenskap och laboratorium
Gentaur
Storlek: 5x0.05mg
Parameters
| Storage and shipping | Ships on blue ice. Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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Z500184
Recombinant Human ITK (352-end) (N-GST tag)
ITK is a member of the TEC family of non-receptor tyrosine kinases. ITK is expressed in T-cells and is important for T-cell development and activation through the antigen receptor. ITK require prior activation of Lck, Zap-70 and PI3-kinase for efficient activation and shares major substrates with both Lck and Zap-70 . ITK knockout mice show multiple effects on T cell development, cytokine production and T-helper cell differentiation. T cells that lack or express mutant versions of ITK show impaired TCR-induced actin polymerization, cell polarization and regulation of the signaling events involved in cytoskeletal reorganization .
671 €
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