Recombinant Mouse FGFR4 / CD334 Protein (His tag)

MBS2547108-01mg

Recombinant Mouse FGFR4 / CD334 Protein (His tag)

1198.62 €

MBS2547108-5x01mg

Recombinant Mouse FGFR4 / CD334 Protein (His tag)

4730.38 €

PKSM040810-100ug

Recombinant Mouse FGFR4/CD334 Protein (His Tag)

Mouse

77288 €

NCP0361

CD334 Recombinant Protein

Fibroblast growth factors (FGFs) produce mitogenic and angiogenic effects in target cells by signaling through cell surface receptor tyrosine kinases. There are four members of the FGF receptor family: FGFR1 (flg), FGFR2 (bek, KGFR), FGFR3, and FGFR4. Each receptor contains an extracellular ligand binding domain, a transmembrane domain, and a cytoplasmic kinase domain. Following ligand binding and dimerization, the receptors are phosphorylated at specific tyrosine residues. Seven tyrosine residues in the cytoplasmic tail of FGFR1 can be phosphorylated: Tyr463, 583, 585, 653, 654, 730, and 766. Tyr653 and Tyr654 are important for catalytic activity of activated FGFR and are essential for signaling. The other phosphorylated tyrosine residues may provide docking sites for downstream signaling components such as Crk and PLCγ.

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Fgfr4-710MF

Recombinant Mouse Fgfr4 Protein, Fc/His-tagged, FITC conjugated

Store it under sterile conditions at -20 to -70 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

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E40KMP1161

Recombinant Human FGFR4/FGF Receptor 4 Protein, Fc & His Tag

892.5 €