Katalognummer: 965 - JOT-PR1065
Produktkategori: Företag och industri > Vetenskap och laboratorium
Storlek: 10µg
Additional information | Interleukin 2 is a protein that has a variety of immunologic functions, the most notable being the ability of IL-2 to promote the proliferation and maturation of activated T cells. A comparison of the amino acid sequences of human and murine IL-2 shows an approximately 60% sequence similarity, and human sequence IL-2 has been found to be active on murine cell lines. Some of the biological activities attributed to IL-2 include:● induction of secretion of interferon-γ and tumor necrosis factors -α and -β from peripheral blood mononuclear cells● stimulation of the rate of synthesis of c-myc RNA and transferrin receptor● activation of neutrophils● stimulation of proliferation and maturation of activated helper T cells● stimulation of proliferation of activated and natural killer cells and tumor-infiltrating lymphocytes, as well as enhancement of the ability of these cytotoxic lymphocytes to kill target cells● induction of the expression of IL-2 receptors on T cells● stimulation of proliferation of antibody-producing B cells |
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