Recombinant (E.Coli) Human CD2

356061

BD Bfgf human recombinant ecoli - PK10

3494.4 €

AP60095

Recombinant Human Interferon-alpha2b, Ecoli.

1287 €

P1300-.1

Recombinant Human Interferon-alpha2b, Ecoli.

Peptides & Proteins|Recombinant Proteins

620.6 €

E43CP0333

CD2 Recombinant Protein

1020 €

NCP0333

CD2 Recombinant Protein

CD2 is a transmembrane glycoprotein expressed early in thymocyte development and present on most circulating T cells. CD2 plays a role in T cell adhesion through binding to its ligand CD58 (LFA-3). Stimulation of CD2 also leads to T cell activation and proliferation. T cells from mice deficient in both CD2 and CD28 have severe defects in T cell activation and function, while T cells deficient in either CD2 or CD28 are still capable of mounting a response, suggesting that CD2 and CD28 may have overlapping functions and may be able to compensate for each other. In addition, engagement of CD2 and CD58 was recently demonstrated to be the primary costimulatory signal in T cells that lack CD28. CD2 expression also distinguishes a subset of plasmacytoid dendritic cells found in tumors and tonsils that express lysozyme, higher levels of IL-12 p40, and higher levels of CD80.

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PROTP06729-2

Human, CD2 Human Recombinant Protein, sf9

CD2 Human Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 194 amino acids (25-209a.a.) and having a molecular mass of 22.3kDa (Molecular size on SDS-PAGE will appear at approximately 28-40 kDa).;CD2 is expressed with a 6 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.

720.6 €