Purified Anti-Human CD22 Monoclonal Antibody

DL20664F-100ug

Purified Anti-Human CD22 Monoclonal Antibody

CD22 is a 130 kD type I transmembrane glycoprotein also known as Siglec-2 and BL-CAM. It is a member of the immunoglobulin superfamily (sialoadhesion subgroup). CD22 is expressed in the cytoplasm of pro-B and pre-B cells, and on the surface of mature B and activated B cells, but not on plasma cells. CD22 is present in the B cell receptor complex and associates with SHP-1, Syk, Lck, Lyn, and phospholipase Cγ1. A primary function of CD22 is thought to be in limiting antigen receptor signaling by modulating B cell activation threshold. CD22 has been shown to bind to CD45RO and CD75, although the natural ligands for this molecule remain controversial.

937.5 €

DL20664F-25ug

Purified Anti-Human CD22 Monoclonal Antibody

CD22 is a 130 kD type I transmembrane glycoprotein also known as Siglec-2 and BL-CAM. It is a member of the immunoglobulin superfamily (sialoadhesion subgroup). CD22 is expressed in the cytoplasm of pro-B and pre-B cells, and on the surface of mature B and activated B cells, but not on plasma cells. CD22 is present in the B cell receptor complex and associates with SHP-1, Syk, Lck, Lyn, and phospholipase Cγ1. A primary function of CD22 is thought to be in limiting antigen receptor signaling by modulating B cell activation threshold. CD22 has been shown to bind to CD45RO and CD75, although the natural ligands for this molecule remain controversial.

375 €

E16FHU0221-100U

Purified anti-human CD22

Available in various conjugation types.

436 €

MBS8502707-01mLAF546

Mouse Anti-Human CD22, Purified mAb

777.88 €

MBS8502707-01mLAF750

Mouse Anti-Human CD22, Purified mAb

777.88 €

MBS8502707-100Tests

Mouse Anti-Human CD22, Purified mAb

573.88 €