PROTAC CDK12/13 Degrader-1 (TFA)

HY-151110A

PROTAC CDK12/13 Degrader-1 (TFA)

PROTAC CDK12/13 Degrader-1 (7f) TFA is a highly selective cell cycle protein-dependent kinase CDK12/CDK13 dual degrader with the DC50 values of 2.2 nM and 2.1 nM, respectively. PROTAC CDK12/13 Degrader-1 TFA has anti-proliferative activity and can be used in breast cancer research[1].

5389.76 €

HY-103628

PROTAC CDK9 Degrader-1

PROTAC CDK9 Degrader-1 is a PROTAC connected by ligands for Cereblon and CDK as a selective CDK9 degrader.

2974.14 €

MBS5758225-10mg

PROTAC CDK9 Degrader-1

892.62 €

HY-115729A

(R)-PROTAC CDK9 ligand-1

(R)-PROTAC CDK9 ligand-1 (Compound 19.4) is a CDK9-targeting degrader that can be used to synthesize PROTAC with antitumor activity[1].

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HY-145737A

PROTAC SOS1 degrader-1 (TFA)

PROTAC SOS1 degrader-1 (TFA) is a potent PROTAC SOS1 degrader with an DC50 of 98.4 nM. PROTAC SOS1 degrader-1 shows antiproliferation activity in cancer cells with various KRAS mutations. PROTAC SOS1 degrader-1 shows antitumor effect with low toxicity[1].

1558.53 €

HY-111848A

PROTAC AR Degrader-4 (TFA)

PROTAC AR Degrader-4 comprises a IAP ligand binding group, a linker and an Androgen Receptor (AR) binding group. PROTAC AR Degrader-4 is an AR degrader. Degradation inducers based on cIAP1 are called specific and non-genetic IAP-dependent protein erasers (SNIPERs)[1].

1948.15 €