PROTAC BRD4 Degrader-13

HY-138636

PROTAC BRD4 Degrader-13

PROTAC BRD4 Degrader-13 (compound 9d) is a PROTAC connected by ligands for von Hippel-Lindau and BRD4. PROTAC BRD4 Degrader-13 can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with a DC50 of 0.025 nM and 6.0 nM, respectively[1].

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MBS5800387-INQUIRE

PROTAC BRD4 Degrader-13

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T40075-10mg

PROTAC BRD4 Degrader-13

PROTAC BRD4 Degrader-13

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HY-155393

PROTAC BRD4 Degrader-22

PROTAC BRD4 Degrader-22 (Compd 44h) is a PROTAC-based BRD4 degrader, with a pDC50 (MOLT4, 24 h) of 9.2[1].

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HY-156566

PROTAC BRD4 Degrader-21

PROTAC BRD4 Degrader-21 (Comp 74) is a PROTAC degrader of BRD4. PROTAC BRD4 Degrader-21 displays significant tumor growth inhibition in tumor -bearing xenograft models in mice and can be used for anticancer research[1].

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HY-161093

PROTAC BRD4 Degrader-23

PROTAC BRD4 Degrader-23 (compound 17) is aneffective visible-light-controlled degrader. PROTAC BRD4 Degrader-23 caninhibit tumor cell proliferation under 405 nm light irradiation[1].

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