
Katalognummer: 965 - JOT-AP07383-100ul
Produktkategori: Företag och industri > Vetenskap och laboratorium
Storlek: 100ul
| Additional information | The protein encoded by MAPKAPK5 (mitogen-activated protein kinase-activated protein kinase 5) is a tumor suppressor and member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. The encoded protein is found in the nucleus but translocates to the cytoplasm upon phosphorylation and activation. This kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately spliced transcript variants of MAPKAPK5 encoding distinct isoforms have been reported. |
|---|

By: Author , 2 Comment
30 August 2025

By: Author , 2 Comment
23 August 2025

By: Author , 2 Comment
16 August 2025

By: Author , 2 Comment
8 August 2025