Phospho-Caveolin 2 (Ser23) Antibody

AF8104

Phospho-Caveolin 2 (Ser23) Antibody

Human,Mouse,Rat,Monkey

520 €

AF8104

Phospho-Caveolin 2 (Ser23) Antibody

960 €

AF8104-100ul

Phospho-Caveolin 2 (Ser23) Antibody

WB,IHC,ELISA(peptide)

394 €

JOT-PHS00050-100ul

Phospho-Caveolin-1 (Y14) Polyclonal Antibody

Human;mouse;rat

480 €

JOT-PHS00050-50ul

Phospho-Caveolin-1 (Y14) Polyclonal Antibody

Human;mouse;rat

366 €

BT-PHS00050-100ul

Phospho-Caveolin-1 (Y14) Polyclonal Antibody

The scaffolding protein (caveolin 1) encoded by CAV1 is the main component of the caveolae plasma membranes found in most cell types. Caveolin 1 links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. CAV1 is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in CAV1 have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.

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