PD-L1 Recombinant Antibody AE00385

AE00385-02mg

PD-L1 Recombinant Antibody AE00385

923.6 €

AE00385-1mg

PD-L1 Recombinant Antibody AE00385

2570 €

91-293

PD-L1 Recombinant Protein

CD274, also known as B7-H1 or programmed death ligand 1 (PD-L1), is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin receptor superfamily. Programmed death-1 ligand-1 (PD-L1, CD274, B7-H1) has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune responses and peripheral tolerance. By binding to PD1 on activated T-cells and B-cells, PD-L1 may inhibit ongoing T-cell responses by inducing apoptosis and arresting cell-cycle progression. Accordingly, it leads to growth of immunogenic tumor growth by increasing apoptosis of antigen specific T cells and may contribute to immune evasion by cancers. PD-L1 thus is regarded as promising therapeutic target for human autoimmune disease and malignant cancers.

738.4 €

MBS346028-02mL

PD-L1 Antibody

797 €

MBS346028-05mL

PD-L1 Antibody

1262.38 €

MBS346028-1mL

PD-L1 Antibody

1823.38 €