PD-161570
415.65 EUR
415.65 EUR
In Stock
quantity
Produktdetaljer
Katalognummer: 804 - HY-100434
Produktkategori: Företag och industri > Vetenskap och laboratorium
Leverantör:
Gentaur
Storlek: 1 mg
Parameters
| Storage and shipping | -20°C, 3 years; 4°C, 2 years (Powder) |
|---|
HY-100434
PD-161570
PD-161570 is a potent and ATP-competitive human FGF-1 receptor inhibitor with an IC50 of 39.9 nM and a Ki of 42 nM. PD-161570 also inhibits the PDGFR, EGFR and c-Src tyrosine kinases with IC50 values of 310 nM, 240 nM, and 44 nM, respectively. PD-161570 inhibits PDGF-stimulated autophosphorylation and FGF-1 receptor phosphorylation with IC50s of 450 nM and 622 nM, respectively[1][2]. PD-161570 is also a bone morphogenetic proteins (BMPs) and TGF-β signaling inhibitor[3].
415.65 €
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