OKEH01206-96W - TNNT3 ELISA Kit (Human)

OKEH01206-96W

OKEH01206-96W - TNNT3 ELISA Kit (Human)

944.5 €

OKEH01206

TNNT3 ELISA Kit (Human) (OKEH01206)

Description of target: The binding of Ca(2+) to the trimeric troponin complex initiates the process of muscle contraction. Increased Ca(2+) concentrations produce a conformational change in the troponin complex that is transmitted to tropomyosin dimers situated along actin filaments. The altered conformation permits increased interaction between a myosin head and an actin filament which, ultimately, produces a muscle contraction. The troponin complex has protein subunits C, I, and T. Subunit C binds Ca(2+) and subunit I binds to actin and inhibits actin-myosin interaction. Subunit T binds the troponin complex to the tropomyosin complex and is also required for Ca(2+)-mediated activation of actomyosin ATPase activity. There are 3 different troponin T genes that encode tissue-specific isoforms of subunit T for fast skeletal-, slow skeletal-, and cardiac-muscle. This gene encodes fast skeletal troponin T protein; also known as troponin T type 3. Alternative splicing results in multiple transcript variants encoding additional distinct troponin T type 3 isoforms. A developmentally regulated switch between fetal/neonatal and adult troponin T type 3 isoforms occurs. Additional splice variants have been described but their biological validity has not been established. Mutations in this gene may cause distal arthrogryposis multiplex congenita type 2B (DA2B).;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 7.2 pg/mL

1348.6 €

OKEH03393-96W

OKEH03393-96W - TNNT3 ELISA Kit (Rat)

944.5 €

OKEH08135-96W

OKEH08135-96W - PC ELISA Kit (Human)

1357 €

OKEH08183-96W

OKEH08183-96W - GK ELISA Kit (Human)

1357 €

OKEH01889-96W

OKEH01889-96W - IK ELISA Kit (Human)

1094.5 €