OKCD03455-96W - FGF1 Chemi-Luminescent ELISA Kit (Rat)

OKCD03455-96W

OKCD03455-96W - FGF1 Chemi-Luminescent ELISA Kit (Rat)

1469.5 €

OKCD05512-96W

OKCD05512-96W - FGF1 Chemi-Luminescent ELISA Kit (Pig)

1670.5 €

OKCD03455

FGF1 Chemi-Luminescent ELISA Kit (Rat) (OKCD03455)

Description of target: Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrin ITGAV:ITGB3. Its binding to integrin, subsequent ternary complex formation with integrin and FGFR1, and the recruitment of PTPN11 to the complex are essential for FGF1 signaling. Induces the phosphorylation and activation of FGFR1, FRS2, MAPK3/ERK1, MAPK1/ERK2 and AKT1. Can induce angiogenesis.;Species reactivity: Rat;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 31.25 pg/mL

2075.8 €

OKCD03955-96W

OKCD03955-96W - TH Chemi-Luminescent ELISA Kit (Rat)

1469.5 €

OKCD05538-96W

OKCD05538-96W - MB Chemi-Luminescent ELISA Kit (Rat)

1544.5 €

OKCD03294-96W

OKCD03294-96W - GPT Chemi-Luminescent ELISA Kit (Rat)

1469.5 €