OKCD01444-96W - IGF1 ELISA Kit (Guinea pig )

OKCD01444-96W

OKCD01444-96W - IGF1 ELISA Kit (Guinea pig )

1207 €

OKCD05749-96W

OKCD05749-96W - IGF1 ELISA Kit (Pig)

1432 €

OKCD01444

IGF1 ELISA Kit (Guinea pig ) (OKCD01444)

Description of target: The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca2+-dependent exocytosis of IGF1 is required for sensory perception of smell in the olfactory bulb. Acts as a ligand for IGF1R. Binds to the alpha subunit of IGF1R, leading to the activation of the intrinsic tyrosine kinase activity which autophosphorylates tyrosine residues in the beta subunit thus initiatiating a cascade of down-stream signaling events leading to activation of the PI3K-AKT/PKB and the Ras-MAPK pathways. Binds to integrins ITGAV:ITGB3 and ITGA6:ITGB4. Its binding to integrins and subsequent ternary complex formation with integrins and IGFR1 are essential for IGF1 signaling. Induces the phosphorylation and activation of IGFR1, MAPK3/ERK1, MAPK1/ERK2 and AKT1.;Species reactivity: Guinea Pig ;Application: ;Assay info: Assay Methodology: Quantitative Sandwich Immunoassay;Sensitivity: < 33 pg/mL

1699.6 €

OKCD05758-96W

OKCD05758-96W - IGFBP2 ELISA Kit (Bovine)

1432 €

OKCD05762-96W

OKCD05762-96W - IGFBP3 ELISA Kit (Bovine)

1432 €

OKCD08215-96W

OKCD08215-96W - IGFBP5 ELISA Kit (Bovine)

1432 €