Mouse VEGF R2 / KDR Protein, Mouse IgG2a Fc Tag, low endotoxin
3078.6 EUR
In Stock
quantity
Produktdetaljer
Katalognummer: 716 - VE2-M5258
Produktkategori: Företag och industri > Vetenskap och laboratorium
Gentaur
Storlek: 100ug
Parameters
| Additional information | Kinase insert domain receptor (KDR) is also known as CD309, FLK1, VEGFR, VEGFR2, and is one of the subtypes of VEGFR. VEGF receptors are receptors for vascular endothelial growth factor (VEGF). There are three main subtypes of VEGFR, numbered 1, 2 and 3. The VEGF receptors have an extracellular portion consisting of 7 immunoglobulin-like domains, a single transmembrane spanning region and an intracellular portion containing a split tyrosine-kinase domain. VEGF-A binds to VEGFR-1 (Flt-1) and VEGFR-2 (KDR/Flk-1). VEGFR-2 appears to mediate almost all of the known cellular responses to VEGF.The function of VEGFR-1 is less well defined, although it is thought to modulate VEGFR-2 signaling. Another function of VEGFR-1 may be to act as a dummy/decoy receptor, sequestering VEGF from VEGFR-2 binding (this appears to be particularly important during vasculogenesis in the embryo). In addition, VEGFR2 is able to interact with HIV-1 extracellular Tat protein upon VEGF activation, and seems to enhance angiogenesis in Kaposi's sarcoma lesions. |
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| Storage and shipping | -20℃ RT |
VE2-M5258
Mouse VEGF R2 / KDR Protein, Mouse IgG2a Fc Tag, low endotoxin
Mouse VEGF R2 Protein, Mouse IgG2a Fc Tag (VE2-M5258) is expressed from human 293 cells (HEK293). It contains AA Ala 20 - Glu 762 (Accession # P35918-1).
3078.6 €
FL4-M5251
Mouse VEGF R3 / FLT4 Protein, Mouse IgG2a Fc Tag, low endotoxin
Mouse VEGF R3 Protein, Mouse IgG2a Fc Tag (FL4-M5251) is expressed from human 293 cells (HEK293). It contains AA Tyr 25 - Asp 770 (Accession # P35917-1).
3562.56 €
CD0-H525a
Human CD40 / TNFRSF5 Protein, Mouse IgG2a Fc Tag, low endotoxin (MALS verified)
Human CD40 Protein, Mouse IgG2a Fc Tag (CD0-H525a) is expressed from human 293 cells (HEK293). It contains AA Glu 21 - Arg 193 (Accession # P25942-1).
3078.6 €
RAK-H5251
Human RANK / TNFRSF11A Protein, Mouse IgG2a Fc Tag, low endotoxin (MALS verified)
Human RANK Protein, Mouse IgG2a Fc Tag (RAK-H5251) is expressed from human 293 cells (HEK293). It contains AA Ile 30 - Pro 212 (Accession # Q9Y6Q6-1).
3248.64 €
CD7-C5259
Cynomolgus / Rhesus macaque CD27 / TNFRSF7 Protein, Mouse IgG2a Fc Tag, low endotoxin
Cynomolgus / Rhesus macaque CD27 Protein, Mouse IgG2a Fc Tag (CD7-C5259) is expressed from human 293 cells (HEK293). It contains AA Ala 20 - Arg 191 (Accession # XP_005569963.1). In the region Ala 20 - Arg 191, the AA sequence of Cynomolgus and Rhesus macaque CD27 are homologus.
3562.56 €
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