Methyltetrazine-DBCO
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0.01 EURAsk for quotation
On request
quantity
Produktdetaljer
Katalognummer: 931 - T16056-10mg
Produktkategori: Företag och industri > Vetenskap och laboratorium
Leverantör:
Gentaur
Storlek: 10mg
Parameters
| Additional information | SMILES: O=C(NCC(C(=O)NCCCOC=1C=CC(=CC1)C2=NN=C(N=N2)C)S(=O)(=O)O)CCC(=O)N3C=4C=CC=CC4C#CC=5C=CC=CC5C3; Formula: C34H33N7O7S |
|---|
HY-140313
Methyltetrazine-DBCO
Methyltetrazine-DBCO is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Methyltetrazine-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Methyltetrazine-DBCO also contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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