Methyltetrazine-DBCO
600 EUR
600 EUR
In Stock
quantity
Produktdetaljer
Katalognummer: 940 - 572282
Produktkategori: Företag och industri > Vetenskap och laboratorium
Leverantör:
Gentaur
Storlek: 10.0mg
Parameters
| Additional information | Smiles Code: O=C(CCC(NCC(S(=O)(O)=O)C(NCCCOC1=CC=C(C2=NN=C(C)N=N2)C=C1)=O)=O)N3CC4=C(C=CC=C4)C#CC5=C3C=CC=C5 |
|---|
HY-140313
Methyltetrazine-DBCO
Methyltetrazine-DBCO is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Methyltetrazine-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Methyltetrazine-DBCO also contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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