L-685458 (L-685,458; L685458; L 685458)
2639.38 EUR
2639.38 EUR
In Stock
quantity
Produktdetaljer
Katalognummer: 544 - MBS131513-100mg
Produktkategori: Företag och industri > Vetenskap och laboratorium
Leverantör:
Gentaur
Storlek: 100mg
Parameters
| Storage and shipping | For long term storage, store product at -20 degree C. |
|---|
HY-19369
L-685458
L-685458 is a potent transition state analog (TSA) γ-secretase inhibitor (GSI). L-685458 inhibits amyloid β-protein precursor γ-secretase activity with IC50 of 17 nM, shows greater than 50-100-fold selectivity over other aspartyl proteases tested. L685458 inhibits γ-secretase-mediated cleavage of APP-C99 and Notch-100 with IC50s of 301.3 nM and 351.3 nM, respectively. L-685458 can be used for the research of alzheimer’s disease (AD) and cancers[1][2].
2532.57 €
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