The STAT3 Reporter Jurkat cell line is designed for monitoring the STAT3 signal transduction pathway. It contains a firefly luciferase gene driven by STAT3 response elements located upstream of the minimal TATA promoter. After activation by cytokines or growth factors, endogenous STAT3 binds to the DNA response elements, inducing transcription of the luciferase reporter gene.
The STAT3 Reporter (eGFP)-HEK293 cell line is designed to monitor the STAT3 signal transduction pathway. It contains an eGFP gene driven by STAT3 response elements located upstream of the minimal TATA promoter. After activation by cytokines and growth factors, endogenous STAT3 binds to the DNA response elements, inducing transcription of the eGFP reporter gene.
Human Gli Reporter Cell Line is derived from NIH3T3. This reporter cell line can be used as the following application: • Monitor Hedgehog signaling pathway activity. • Screen for activators or inhibitors of the Hedgehog signaling pathway.
Human GR-GAL4 Reporter Cell Line is an ideal product to monitor glucocorticoid signaling pathway activity and screen activators or inhibitors of the glucocorticoid signaling pathway.
Human Hido1 Reporter Cell line is derived from HEK293. This reporter cell line is used for monitoring IDO1 pathway activity and screening for activators or inhibitors of IDO1 in a cellular context