Human GR-GAL4 Reporter Cell Line
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Catalog number: 870 - ABC-RC0091
Product Category: Business & Industrial > Science & Laboratory
Gentaur
Size: 1 vial
ABC-RC0091
Human GR-GAL4 Reporter Cell Line
Human GR-GAL4 Reporter Cell Line is an ideal product to monitor glucocorticoid signaling pathway activity and screen activators or inhibitors of the glucocorticoid signaling pathway.
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78525
GR-GAL4 Luciferase Reporter Jurkat Cell Line
The Glucocorticoid Receptor (GR)-GAL4 Luciferase Reporter Jurkat Cell Line contains an engineered transcription factor stably integrated into the genome of Jurkat cells, which consists of the glucocorticoid receptor ligand binding domain fused to the DNA binding domain of GAL4. This fusion construct activates firefly luciferase expression which is under the control of a multimerized GAL4 upstream activation sequence (UAS). This allows for specific detection of glucocorticoid-induced activation of the glucocorticoid receptor without the need for individual transcriptional targets and with low cross-reactivity for other nuclear receptor pathways. This cell line is validated for response to stimulation of dexamethasone and to the treatment with mifepristone, an inhibitor of the glucocorticoid signaling pathway.
3598.13 €
ABC-RC0086
Human GAL4 Reporter Cell Line
Human GAL4 Reporter Cell Line is an ideal product for monitoring biological activity
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ABC-RC0111
Human NFAT Reporter Cell Line– HEK293
Human NFAT Reporter Cell Line is derived from HEK293. This reporter cell line is an ideal product to monitor the blogical ativity
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ABC-RC0112
Human NFAT Reporter Cell Line–RAW264.7
Human NFAT Reporter Cell Line is derived from RAW264.7. This reporter cell line is an ideal product to monitor the blogical ativity
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ABC-RC0122
Human SRE Reporter Cell Line - HEK293
Human SRE Reporter Cell Line is derived from HEK293. Application: • Monitor MAPK/ERK signaling pathway activity and SRF-mediated activity.• Screen for activators or inhibitors of the MAPK/ERK signaling pathway.