
Katalognummer: 716 - SIR-H5255
Produktkategori: Företag och industri > Vetenskap och laboratorium
Storlek: 100ug
| Additional information | Single immunoglobulin IL-1-related receptor (SIGIRR), which is also known as Toll/interleukin-1 receptor 8, is a member of the interleukin-1 receptor (IL-1R) family. SIGIRR acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4. Through its extracellular domain interferes with the heterodimerization of Il1R1 and IL1RAP. |
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| Storage and shipping | -20℃ RT |

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