
Katalognummer: 749 - KTE61317-48T
Produktkategori: Företag och industri > Vetenskap och laboratorium
Storlek: 48T
| Additional information | Platelet-activating factor is a potent phospholipid activator and mediator of many leukocyte functions, including platelet aggregation, inflammation, and anaphylaxis.It is produced in response to specific stimuli by a variety of cell types, including neutrophils, basophils, platelets, and endothelial cells.Several molecular species of platelet-activating factor have been identified which vary in the length of the O-alkyl side chain.It is an important mediator of bronchoconstriction.It causes platelets to aggregate and blood vessels to dilate. Thus it is important to the process of hemostasis. At a concentration of 10^-12 M, PAF causes life threatening inflammation of the airways to induce asthma like symptoms.Toxins such as fragments of destroyed bacteria induce the synthesis of PAF, which causes a drop in blood pressure and reduced volume of blood pumped by the heart, which leads to shock and maybe death. |
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| Storage and shipping | Storage: The unopened kit should be stored at 2 - 8°C. After opening, please store refer to protocols.Shipping:Gel pack with blue ice. |

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