Human KRAS (2-185, G12D) Protein, His Tag (active enzyme, MALS verified)
3902.64 EUR
In Stock
quantity
Produktdetaljer
Katalognummer: 716 - KRS-H51H4
Produktkategori: Företag och industri > Vetenskap och laboratorium
Gentaur
Storlek: 50ug
Parameters
| Additional information | KRAS (Kirsten rat sarcoma 2 viral oncogene homolog) gene is a proto-oncogene that encodes a small GTPase transductor protein called KRAS. KRAS is also known as Ki-Ras, c-K-ras andc-Ki-ras. Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the regulation of cell proliferation, promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs) in colorectal cancer (CRC) cells in a ZNF304-dependent manner. RAS is one of the most frequently mutated oncogenes in human cancer but the frequency and distribution of RAS gene mutations are not uniform. In details, mutation of glycine 12 (G12) causes RAS activation by interfering with GAP binding and GAP-stimulated GTP hydrolysis. The reference shows the pathway may as a potential therapy targets. |
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| Storage and shipping | -20℃ RT |
KRS-H51H4
Human KRAS (2-185, G12D) Protein, His Tag (active enzyme, MALS verified)
Human KRAS (2-185,G12D), His Tag (KRS-H51H4) is expressed from E. coli cells. It contains AA Thr 2 - Cys 185 (Accession # P01116-2 (G12D)).
3902.64 €
SER-H52H5
Human Serpin G1 / C1 inhibitor Protein, His Tag (active enzyme, MALS verified)
Human Serpin G1 Protein, His Tag (SER-H52H5) is expressed from human 293 cells (HEK293). It contains AA Asn 23 - Ala 500 (Accession # P05155-1).
567.24 €
FIX-H52H3
Human Coagulation factor IX / F9 Protein, His Tag (active enzyme, MALS verified)
Human Coagulation factor IX Protein, His Tag (FIX-H52H3) is expressed from human 293 cells (HEK293). It contains AA Thr 29 - Thr 461 (Accession # P00740-1).
7604.28 €
TF7-H52H5
Human Coagulation factor VII / F7 Protein, His Tag (active enzyme, MALS verified)
Human Coagulation factor VII, His Tag (TF7-H52H5) is expressed from human 293 cells (HEK293). It contains AA Ala 61 - Pro 466 (Accession # P08709-1).
8336.76 €
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