Human IDH1 Protein, His Tag (active enzyme, MALS verified)
5389.12 EUR
In Stock
quantity
Produktdetaljer
Katalognummer: 716 - ID1-H51H6
Produktkategori: Företag och industri > Vetenskap och laboratorium
Gentaur
Storlek: 20ug
Parameters
| Additional information | The IDH enzymes catalyze the oxidative decarboxylation of isocitrate to alpha-ketoglutarate (α-KG), producing nicotinamide adenine dinucleotide phosphate (NADPH) in the process via the citric acid cycle. Eukaryotic cells express two distinct classes of IDHs that utilize either NAD or NADP as their cofactors and serve diverse biological functions. NAD-dependent IDH is localized to the mitochondrial matrix and is well known for its central role for energy production in the Krebs cycle. NADP-dependent IDHs are primarily located either in mitochondria or cytoplasm . Each NADP-dependent isozyme is a homodimer. Mutations of Arg132 of human IDH1 result in a reduced ability of the enzyme to convert isocitrate to alpha ‑ketoglutarate, but the enzyme acquires the ability to generate 2-hydroxyglutarate (2HG) from alpha‑ketoglutarate，2-HG is elevated in several tumor types, including a subset of AMLs. |
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| Storage and shipping | -70℃ Dry ice |
| Storage and shipping | With |
ID1-H51H6
Human IDH1 Protein, His Tag (active enzyme, MALS verified)
Human IDH1, His Tag (ID1-H51H6) is expressed from E. coli cells. It contains AA Met 1 - Leu 414 (Accession # O75874-1).
5389.12 €
ID1-H51H8
Human IDH1 (R132C) Protein, His Tag (MALS verified)
Human IDH1 (R132C), His Tag (ID1-H51H8) is expressed from E. coli cells. It contains AA Met 1 - Leu 414 (Accession # O75874-1(R132C)).
4931.32 €
ALL-H52H3
Human ALPL Protein, His Tag (active enzyme, MALS verified)
Human ALPL Protein, His Tag (ALL-H52H3) is expressed from human 293 cells (HEK293). It contains AA Leu 18 - Ser 502 (Accession # P05186-1).
3741.04 €
CD1-M53H3
Mouse CD39L1 / ENTPD2 Protein, His Tag (active enzyme, MALS verified)
Mouse CD39L1 / ENTPD2 Protein, His Tag (CD1-M53H3) is expressed from CHO cells. It contains AA Cys 26 - Ser 462 (Accession # O55026-1).
758.8 €
EN3-M52H3
Mouse ENPP3 / CD203c Protein, His Tag (active enzyme, MALS verified)
Mouse ENPP3, His Tag (EN3-M52H3) is expressed from human 293 cells (HEK293). It contains AA Arg 46 - Ile 874 (Accession # Q6DYE8-1).
3562.56 €
MM8-M52H7
Mouse MMP-8 Protein, His Tag (active enzyme, MALS verified)
Mouse MMP-8 Protein, His Tag (MM8-M52H7) is expressed from human 293 cells (HEK293). It contains AA Phe 21 - Gly 262 (Accession # O70138-1).
758.8 €
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