Human FLT3 Ligand

ELK1021-48T

HumanFlt3L(FMSLikeTyrosineKinase3Ligand)ELISAKit

Sandwich

966.5 €

ELK1021-96T

HumanFlt3L(FMSLikeTyrosineKinase3Ligand)ELISAKit

Sandwich

1049 €

90137-A

Human FLT3 Ligand

Recombinant FLT-3 Ligand is a disulfide-linked monomeric protein consisting of 156 amino acid residues, and migrates as an approximately 17 kDa protein under non-reducing conditions and reducing conditions in SDS-PAGE. Optimized DNA sequence encoding human FLT-3 ligand mature chain was expressed in E. coli.

345 €

Z100229

Recombinant Human FLT3 Ligand (FLT3LG)

FLT-3 ligand promotes long- term expansion and differentiation of human pro-B cells in the presence of IL-7 or in combination of IL-7 and IL-3. The human flt-3 ligand also stimulates the proliferation of cells expressing murine flt-3 receptors. In combination with SCF and IL3, flt-3 ligand can cause expansion of cells with the marker spectrum CD34(+) CD38(-). Alone, flt- 3 ligand supports the survival of precursors in the lineage of blood-forming cells such as CFU-GM, CFU- GEMM, and the very primitive high proliferative potential colony-forming cells, HPP-CFC. flt-3 ligand only has marginal effects on progenitors for erythroid cells and megakaryocytes.

7766 €

PROTP49771-5

Recombinant Human Flt3-Ligand Protein

Flt3-Ligand is a growth factor that regulates proliferation of early hematopoietic cells. Flt3-Ligand binds to cells expressing the tyrosine kinase receptor Flt3. Flt3-Ligand, by itself does not stimulate proliferation of early hematopoietic cells, but synergizes with other CSFs and interleukins to induce growth and differentiation. Unlike SCF, Flt3-Ligand exerts no activity on mast cells. Multiple isoforms of Flt3-Ligand have been identified. The predominant biologically active form is anchored to the cell surface as the extracellular domain of a transmembrane protein (209 a.a.). The membrane-bound isoform can be proteolytically cleaved to generate a biologically active soluble isoform. Recombinant human Flt3-Ligand is a soluble 17.6 kDa protein consisting of 155 amino acid residues.

720.6 €

MBS9718673-001mg

Human Flt3 Ligand Protein, His Tag

637.62 €