Human Choroid Plexus Epithelial Cells.

ABC-TC3568

Human Choroid Plexus Epithelial Cells

The choroid plexus epithelial cells (CPEpiC) are the structural basis, form a selective barrier between the nervous system and the blood, and secrete cerebrospinal fluid into the ventricles of the brain. CPEpiC express inward-rectifying anion channels which are thought to have an important role in the secretion of cerebrospinal fluid. CPEpiC synthesize and secrete many growth factors and other peptides that are of trophic benefit following injury to regions of the cerebroventricular system. For example, several growth factors are upregulated in choroid plexus after ischemic and traumatic insults to the central nervous system. The presence of numerous types of growth factor receptors in choroid plexus allows growth factor mediation of recovery processes by autocrine and paracrine mechanisms. CPEpiC culture has been widely used to evaluate their morphological and physiological properties, and its capacity to serve as an in vitro model to access the cellular mechanisms of organic cation transport across the cerebrospinal fluid-blood barrier.HCPEpiC from Gentaur Research Laboratories are isolated from human choroid plexus. HCPEpiC are cryopreserved after purification and delivered frozen. Each vial contains 5×10^5 cells in 1 ml volume. HCPEpiC are characterized by immunofluorescent method with antibodies to cytokeratin-18, -19 and vimentin. HCPEpiC are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HCPEpiC are guaranteed to further expand for 15 population doublings in the conditions specified by Gentaur Research Laboratories.

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cAP-0213

Human Choroid Plexus Epithelial Cells.

818.25 €

ABC-TC3567

Human Choroid Plexus Endothelial Cells

The choroid plexus plays a wide range of roles in brain development, maturation, aging process, endocrine regulation, and pathogenesis of certain neurodegenerative diseases. The choroid plexuses consist of a single layer of epithelial cells enclosing a vascular core that together form the blood-cerebrospinal fluid barrier. The choroidal capillary is a single layer of endothelial cells interrupted by "pores" which exhibit a diaphragm between the lumen and the interstitial space. Study shows that choroid plexus endothelial cells express high Glut1 glucose transporter. The high glucose transport densities in choroids plexus endothelial cells is consistent with the suggestion that choroids epithelial and endothelial cells provide a metabolic work capability for maintaining ionic gradients and secretory functions across the blood-cerebrospinal fluid barriers.HCPEC from Gentaur Research Laboratories are isolated from human brain. HCPEC are cryopreserved after purification and delivered frozen. Each vial contains 5×10^5 cells in 1 ml volume. HCPEC are characterized by immunofluorescent method with antibodies to VWF/Factor VIII, CD31(PCAM) and by uptake of DiI-Ac-LDL. HBMEC are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HCPEC are guaranteed to further expand for 15 population doublings in the condition provided by Gentaur Research Laboratories.

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ABC-TC3811

Human Small Airway Epithelial Cells

The small airways are located at the interface between alveoli and conducting airways. Airway epithelial cells forming a continuous lining to the airways play a unique role as a protective physical and functional barrier to external deleterious agents. These cells function in the regulation of immune responses by contributing to host defense through chemokine production, adhesion molecule expression, and possibly antigen presentation via HLA-DR expression. They also produce liquids contributing to pulmonary fluid balance. Many airway diseases, such as asthma, bronchiolitis, chronic obstructive pulmonary disease, and cystic fibrosis, involve damage to the airway surface epithelium. The human small airway epithelial cell culture may identify new therapeutic options in preventing amplified airway ailment and remodeling.HSAEpiC from Gentaur Research Laboratories are isolated from human lung tissue. HSAEpiC are cryopreserved at either primary culture or passage one culture and delivered frozen. Each vial contains 5×10^5 cells in 1 ml volume. HSAEpiC are characterized by immunofluorescent method with antibodies CK-18, -19, and vimentin. HSAEpiC are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HSAEpiC are guaranteed to further expand for 15 population doublings at the conditions provided by Gentaur Research Laboratories.

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ALHE50

Human Small Airway Epithelial Cells

1180 €

ABC-TC3690

Human Mammary Basal Epithelial Cells

human mammary basal epithelial cells are isolated from mammary tissue of healthy non-diabetic donors between 18 and 60 years old who have undergone elective surgery. The cells are isolated by digestion of the tissue to generate organoid structures.

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