Human B7-H7 / HHLA2, Fc Tag

E24PHA026

Human B7-H7 / HHLA2, Fc Tag

420 €

E24PHA027

Human B7-H7 / HHLA2, His Tag

487.5 €

B77-H5257

Human B7-H7 / HHLA2 Protein, Fc Tag (MALS verified)

Human B7-H7, Fc Tag (B77-H5257) is expressed from human 293 cells (HEK293). It contains AA Ile 23 - Asn 344 (Accession # Q9UM44-1).

3078.6 €

E40KMH718

Recombinant Human B7-H1/PD-L1/CD274 Protein, Fc Tag

892.5 €

E24PCA008

Cynomolgus / Rhesus Macaque B7-H7 / HHLA2, His Tag

487.5 €

11-382

B7-H7 / HHLA2 Recombinant Protein

B7-H7 (HHLA2) is a newly identified B7 family member that regulates human T-cell functions. B7-H7 was previously known as human endogenous retrovirus-H long terminal repeat associating 2 (HHLA2) with unidentified function. Recently, B7-H7 has been identified as a specific ligand for human CD28H. The B7-H7-CD28H pathway strongly promoted CD4+ T-cell proliferation and cytokine production via an AKT-dependent signaling cascade in the presence of TCR signaling, suggesting B7-H7 comprises a new co-stimulatory pathway. The first IgV domain of B7-H7, which presumably binds to a putative receptor, shows the highest homology to other B7 family members.

1106.95 €