FLASH Antibody
2690.38 EUR
In Stock
quantity
Produktdetaljer
Katalognummer: 544 - MBS150625-5x01mg
Produktkategori: Företag och industri > Vetenskap och laboratorium
Gentaur
Storlek: 5x0.1mg
Parameters
| Storage and shipping | FLASH antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
|---|
2271-002mg
FLASH Antibody
FLASH Antibody: A novel mammalian CED-4 homologous was recently identified and cloned in mouse and human and designated FLASH (for FLICE-associated huge protein). FLASH is involved in Fas induced apoptosis. It is recruited to Fas after the receptor cross-linking. Overexpression of wild type of FLASH facilitates and its dominant negative form inhibits Fas induced apoptosis. FLASH interacts with the DEDs of caspase-8 and FADD through the DED-like domain of FLASH and mediates activation of caspase-8. There are parallels between FLASH and Apaf-1/CED-4 although there are arguments against their structural similarity. FLASH is widely expressed.
439.27 €
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