ELISA kit for Rat 27-hydroxycholesterol
777.6 EUR
In Stock
quantity
Produktdetaljer
Katalognummer: 749 - KTE101022-48T
Produktkategori: Företag och industri > Vetenskap och laboratorium
Gentaur
Storlek: 48T
Parameters
| Additional information | 27-Hydroxycholesterol (27-HC) is an endogenous oxysterol with multiple biological functions, including activity as a selective estrogen receptor modulator (SERM) (a mixed, tissue-specific agonist-antagonist of the estrogen receptor (ER)) and as an agonist of the liver X receptor (LXR).It is a metabolite of cholesterol that is produced by the enzyme CYP27A1. A link between high cholesterol and breast cancer has been identified, and it has been proposed that this is due to 27-HC production by CYP27A1.Because of its estrogenic action, 27-HC stimulates the growth of ER-positive breast cancer cells, and has been implicated in limiting the effectiveness of aromatase inhibitors in the treatment of breast cancer.As such, identified CYP27A1 inhibitors, including the marketed drugs anastrozole, fadrozole, bicalutamide, dexmedetomidine, ravuconazole, and posaconazole, have been proposed as potential adjuvant therapies in ER-positive breast cancer. |
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| Storage and shipping | All of the components are shipped on ice packs/blue ice. Upon receiving the kit keep it at +4 degrees Celsius for up to 1 year (refer to the label on the box for the exact expiration date). |
KTE101022-48T
ELISA kit for Rat 27-hydroxycholesterol
Quantitative sandwich ELISA for measuring Rat 27-hydroxycholesterol in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.
777.6 €
KTE101022-5platesof96wells
ELISA kit for Rat 27-hydroxycholesterol
Quantitative sandwich ELISA for measuring Rat 27-hydroxycholesterol in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.
3987 €
KTE101022-96T
ELISA kit for Rat 27-hydroxycholesterol
Quantitative sandwich ELISA for measuring Rat 27-hydroxycholesterol in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.
1150.2 €
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