ELISA kit for Rabbit Platelet-Derived Growth Factor AB (PDGF-AB)
3987 EUR
3987 EUR
In Stock
quantity
Produktdetaljer
Katalognummer: 749 - KTE90071-5platesof96wells
Produktkategori: Företag och industri > Vetenskap och laboratorium
Leverantör:
Gentaur
Storlek: 5 plates of 96 wells
Parameters
| Additional information | Two types of PDGFRs have been identified: alpha type and beta type PDGFRs. The alpha type binds to PDGF-AA, PDGF-BB and PDGF-AB while the beta type PDGFR binds with high affinity to PDGF-BB and PDGF-AB. Upon activation by PDGF, these receptors dimerise, and are "switched on" by auto-phosphorylation of several sites on their cytosolic domains, which serve to mediate binding of cofactors and subsequently activate signal transduction, for example, through the PI3K pathway. The different ligand isoforms have variable affinities for the receptor isoforms, and the receptor isoforms may variably form hetero- or homo- dimers. This leads to specificity of downstream signalling. It has been shown that the cis oncogene is derived from the PDGF B-chain gene. PDGF-BB is the highest-affinity ligand for the PDGFR-beta; PDGFR-beta is a key marker of hepatic stellate cell activation in the process of fibrogenesis. |
|---|---|
| Storage and shipping | All of the components are shipped on ice packs/blue ice. Upon receiving the kit keep it at +4 degrees Celsius for up to 1 year (refer to the label on the box for the exact expiration date). |
KTE90071-48T
ELISA kit for Rabbit Platelet-Derived Growth Factor AB (PDGF-AB)
Quantitative sandwich ELISA for measuring Rabbit Platelet-Derived Growth Factor AB (PDGF-AB) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.
777.6 €
KTE90071-5platesof96wells
ELISA kit for Rabbit Platelet-Derived Growth Factor AB (PDGF-AB)
Quantitative sandwich ELISA for measuring Rabbit Platelet-Derived Growth Factor AB (PDGF-AB) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.
3987 €
Håll dig uppdaterad! Visa tidigare publikationer
By: Author , 2 Comment
Anaplasmos hos hundar och katter – allt du behöver veta
23 August 2025
By: Author , 2 Comment
Solbränna – hur leker man säkert i solen?
16 August 2025
By: Author , 2 Comment
Biologiska läkemedel – Modernitet inom farmaci
1 August 2025
By: Author , 2 Comment
Icke-steroida antiinflammatoriska läkemedel – viktig information om populära läkemedel
22 July 2025