EGFR/C797S-IN-1

HY-152019

EGFR/C797S-IN-1

EGFR/C797S-IN-1 is a potent EGFR-C797S inhibitor with an IC50 value of 0.128 µM. EGFR/C797S-IN-1 shows anti-proliferative activity and anti-tumor activity. EGFR/C797S-IN-1 inhibits the expression of p-EGFR in a dose-dependent manner[1].

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79430

EGFR (C797S) GST-Tag

Recombinant Human EGFR also known as ERBB, mENA, ERBB1, and HER1 with C797S mutation. Genbank Accession NM_005228, a.a. 668-end, with an N-terminal GST-tag, expressed in Sf9 cells via a baculovirus expression system. MW = 100 kDa.

765 €

79454

EGFR (C797A), GST-Tag

Recombinant Human EGFR also known as ERBB, mENA, ERBB1, and HER1 with C797A mutation. Genbank Accession NM_005228, a.a. 695 end, with an N-terminal GST-tag, expressed in Sf9 cells via a baculovirus expression system. MW = 87 kDa.

765 €

HY-19617

EGFR-IN-1

EGFR-IN-1 (compound 24) is an orally active and irreversible L858R/T790M mutant selective EGFR inhibitor. EGFR-IN-1 potently inhibits Gefitinib-resistant EGFR L858R, T790M with 100-fold selectivity over wild-type EGFR. EGFR-IN-1 displays strong antiproliferative activity against the H1975 cells and the first line mutant HCC827 cells. Antitumor activity[1].

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MBS5766570-5mg

EGFR-IN-1

1351.62 €

MBS5766570-5x5mg

EGFR-IN-1

5246.75 €