EGFR-IN-98

HY-161126

EGFR-IN-98

EGFR-IN-98 (Compound 4c) is a EGFR inhibitor. The IC50 values of L858R/T790M/C797S and Del19/T790M/C797S are 0.277 μM and 0.089 μM, respectively. EGFR-IN 98 can be used in the study of tumors[1].

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HY-161146

EGFR-IN-100

EGFR-IN-100 (compound 3f) is a EGFR inhibitor with IC50 range of 0.137-0.507 μM. EGFR-IN-100 has antiproliferative activity and induces the apoptotic pathway. EGFR-IN-100 arrested the MCF-7 cell cycle at the S phase[1].

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MBS5776964-5mg

EGFR-IN-542

1351.62 €

HY-137786

EGFR-IN-16

EGFR-IN-16 (compound 3) is a potent EGFR inhibitor with pIC50 of 4.85 and 4.74 for EGFR and HER-2, respectively[1].

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HY-143445

EGFR-IN-48

EGFR-IN-48 is a potent and orally active EGFR inhibitor with IC50s of 0.193 nM, 0.251 nM, 10.4 nM for EGFRd19/TM/CS, EGFRLR/TM/CS, EGFRWT, respectively. EGFR-IN-48 inhibits the proliferation of BaF3EGFR del19/T790M/C797S and PC-9EGFR del19/T790M/C797S cells with IC50s of 1.526, 66.7 nM, respectively[1].

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HY-143729

EGFR-IN-29

EGFR-IN-29 is a potent EGFR inhibitor, example J-022, extracted from Patent WO2021160087[1].

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