EGFR-IN-52
0.01 EURAsk for quotation
On request
quantity
Produktdetaljer
Katalognummer: 931 - T61646-10mg
Produktkategori: Företag och industri > Vetenskap och laboratorium
Gentaur
Storlek: 10mg
Parameters
| Additional information | SMILES: Cc1c(NC(=S)Nc2ccc3OCOc3c2)c(=O)n(-c2ccccc2)n1C; Formula: C19H18N4O3S |
|---|
HY-146472
EGFR-IN-52
EGFR-IN-52 (Compound 4) is a potent EGFR inhibitor with IC50 values of 0.358, 86.02 and 432.67 µM against EGFR, EGFR L858R-TK and EGFR T790M-TK, respectively. EGFR-IN-52 shows cytotoxic activity against cancer cell lines and induces apoptosis[1].
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HY-142681
EGFR-IN-28
EGFR-IN-28 is a potent EGFR inhibitor. EGFR-IN-28 has antitumor activity[1].
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HY-143337
EGFR-IN-47
EGFR-IN-47 is a potent and orally active EGFRL858R/T790M/C797S inhibitor with an IC50 of 0.01 µM. EGFR-IN-47 induces cell cycle attest and cell apoptosis. EGFR-IN-47 has the potential for the research of NSCLC[1].
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HY-115716
EGFR-IN-17
EGFR-IN-17 is a potent and selective inhibitor of the epidermal growth factor receptor ( IC50 0.0002 μM) to overcome C797S-mediated resistance.
1285.8 €
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